Hans H. Diebner's Research
Systems Biology, Medical Biometry, Immuno-Epidemiological Modelling and AnalysesSince 1st August 2013 I tie in to my postdoctoral research into biometry and biological modelling. I am currently Research Fellow at the IMB-Institute for Medical Informatics and Biometry at the University of Dresden. Research focus is on system biology and mathematical modelling particularly within the scope of theoretical stem cell biology. I will soon report in more detail on my research activities, particularly with respect to modelling of T-cell genesis and dynamics. Key questions concern genesis of oncogenic cells and conditions for the expansion of leukemia/lymphoma.
During my postdoctoral time (1995-1999) at the Department of Medical Biometry in Tübingen the Plasmodium falciparum parasite (Malaria tropica) bothered me most intensively. I contributed with my research within the EU concerted action "Mathematical Models of the Immunological and Clinical Epidemiology of Plasmodium Falciparum Malaria". I am coauthor of three common papers on Malaria dynamics (see below).
Additionally, I contributed in several statistical-biometrical and immuno-epidemiological research projects. Part of my commitment at the institute has been consulting in statistics within the scope of medical research projects of the University of Tübingen. Please find below a publication on the analysis and modelling of a measles epidemic.
Thanks to all fellows of the IMB in Tübingen, including Louis Molineaux, for the amazing time there.
Articles on malaria modelling and an analysis of a measles epidemic:
- Martin Eichner, Hans H. Diebner, Louis Molineaux, William E.Collins, Geoffrey M. Jeffery and Klaus Dietz: Genesis, sequestration and survival of Plasmodium falciparum gametocytes. Parameter estimation from fitting a model to malariatherapy data (pdf), Transactions of the Royal Society of Tropical Medicine and Hygiene 95, 497-501 (2001).
- Louis Molineaux, Hans H. Diebner, Martin Eichner, William E. Collins, Geoffrey M. Jeffery and Klaus Dietz: Plasmodium falciparum parasitaemia described by a new mathematical model (pdf), Parasitology 122, 379-391 (2001).
- Hans H. Diebner, Martin Eichner, Louis Molineaux, William E. Collins, Geoffrey M. Jeffery and Klaus Dietz: Modelling the Transition to Gametocytes from Asexual Blood Stages of Plasmodium falciparum (pdf), J. Theo. Biol. 202, 113-127 (2000).
- M. Eichner, H.H. Diebner, C. Schubert, H.W. Kreth and K. Dietz: Estimation of the time-dependent vaccine efficacy from a measles epidemic. Statistics in Medicine 21, 2355-2368 (2002).